Like the rest of the NPCs of Nazarick, Kyouhukou is absolutely loyal to Ainz.
Albedo views the cockroach with abhorrence like many females in Nazarick.
Shalltear is Kyouhukou's superior and thus, he is her subordinate. However, due to Kyouhukou's race and appearance, Shalltear avoids him and his residence as best she could.
Kyouhukou and Cocytus are friends, sharing a kinship as both are insect-types.
Unlike his sister, Mare does not seem to be afraid of Kyouhukou or his subjects.
Due to Kyouhukou's race and appearance, Aura avoids him and his residence. She doesn't even like the idea of being near one of his subordinates.
Kyouhukou is terrified of her and considers Entoma as a predator of the family, due to her habit of eating other insects. Entoma is the only NPC that willingly visits the Black Capsule, though only to grab a quick snack, much to Kyouhukou's displeasure.
It is unknown how Narberal personally feels about Kyouhukou, but she seems unconcerned when interacting with his subordinates, even feeding one.
Hamsuke is one of the few non-insect monsters unafraid of Kyouhukou. She showed no concern nor disgust when interacting with him or his subjects, even allowing one of them to ride her head to allow it to guide her when she got lost on the 2nd Floor of Nazarick.